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No significant decrease in SSI rate with prophylactic cefazolin in below-knee implant removal
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This report has been verified by one or more authors of the original publication.
JAMA. 2017 Dec 26;318(24):2438-2445
Contributing Authors

JC Goslings B van Dijkman H van den Berg JP Schots MG Dijkgraaf T Schepers SA Dingemans M Backes JM Hoogendoorn P Joosse ED Ritchie WH Roerdink NL Sosef IJB Spijkerman BA Twigt AH van der Veen RN van Veen J Vermeulen DI Vos J Winkelhagen

477 patients who had previously undergone internal fixation for a fracture of the foot, ankle, or lower leg were randomized to either prophylactic cefazolin or saline during routine implant removal. The primary outcome was the development of surgical site infection within 4 weeks of implant removal. Overall, no significant difference in the rate of surgical site infection was observed between the cefazolin group and the saline group.

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Cite this Ace Report

OrthoEvidence. No significant decrease in SSI rate with prophylactic cefazolin in below-knee implant removal . ACE Report. 2018;8(5):14. Available from: https://myorthoevidence.com/AceReport/Report/

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