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AAOS2018: Routine chemoprophylaxis for VTE unnecessary in fractures of tibia and distally

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S Morshed J Patterson

Five randomized controlled trials were included in this meta-analysis comparing the rates of venous thromboembolism and clinically-relevant venous thromboembolism after operative management of fractures in the tibia and distally between chemoprophylaxis groups and control groups. While a significant reduction in the incidence of venous thromboembolism overall was observed with chemoprophylaxis, no significant difference between groups was observed in the incidence of clinically-important venous thromboembolism.

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OrthoEvidence. AAOS2018: Routine chemoprophylaxis for VTE unnecessary in fractures of tibia and distally. ACE Report. 2018;8(3):29. Available from: https://myorthoevidence.com/AceReport/Report/

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