
Arthroplasty
Oral acetaminophen demonstrates similar analgesic efficacy to IV acetaminophen in TKA and THA
Am J Health Syst Pharm. 2018 Mar 15;75(6):367-375515 patients scheduled for total knee or hip arthroplasty were randomized to either oral acetaminophen or intravenous acetaminophen as part of their postoperative analgesia regimen. The primary outcome was opioid use over the first 24 hours after surgery. The main secondary outcome was pain score on a numeric rating scale after 4 and 24 hours. Results demonstrated no significant differences between groups in either opioid use or NRS pain scores.
Unlock the full article
Get unlimited access to OrthoEvidence with a free trial
Start TrialCritical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or continue reading this full article
Register Now

Subscribe to "The Pulse"
Evidence-Based Orthopaedics direct to your inbox.