SPINE
No effect on dysphagia of local DepoMedrol versus saline in anterior cervical discectomy and fusion
This report has been verified
by one or more authors of the
original publication.
J Neurosurg Spine. 2018 Jul;29(1):10-17
121 patients scheduled for single- or multilevel anterior cervical discectomy and fusion were randomized to intraoperative local application or either methylprednisolone 40mg (DepoMedrol) or saline. The primary purpose of this study was to compared patient-reported swallowing function between groups after 6 and 12 weeks. Additional, preveterbral soft-tissue swelling was assessed on sagittal radiographs. Results for the primary outcome demonstrated no significant differences between groups. The swelling index for PSTS demonstrated a significant difference between groups for the mean score at 6 and 12 weeks, but no significant difference was observed in assessment of change from baseline in swelling index after 6 and 12 weeks.
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