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ARTHROPLASTY
NSAIDs associated with reduction in heterotopic ossification development versus placebo in THA
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This report has been verified by one or more authors of the original publication.
Bone Joint J. 2018 Jul;100-B(7):915-922. doi: 10.1302/0301-620X.100B7.BJJ-2017-1467.R1
Contributing Authors

DF Amanatullah M Joice GI Vasileiadis

29 randomized controlled trials were selected for inclusion in this meta-analysis which compared the rates of heterotopic ossification after total hip arthroplasty between groups of patients treated with selective non-steroidal anti-inflammatory drugs (NSAIDs), groups treated with non-selective NSAIDS, and groups treated with placebo. Compared to placebo, both selective and non-selective NSAID groups demonstrated significantly lower rates of heterotopic ossification development. No significant difference between selective and non-selective NSAID groups was observed in the rate of heterotopic ossification development.

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OrthoEvidence. NSAIDs associated with reduction in heterotopic ossification development versus placebo in THA. ACE Report. 2019;9(2):107. Available from: https://myorthoevidence.com/AceReport/Report/

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