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ARTHROPLASTY
Metal ions and moderate pseudotumor development reduced with large- vs. small-head MoM THA
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Bone Joint J. 2018 Aug;100-B(8):1018-1024

185 patients scheduled for metal-on-metal (MoM) total hip arthroplasty (THA) were randomized to either large-head or small-head articulation. Main outcomes of concern in this study included whole blood cobalt and chromium ion concentrations and the incidence of pseudotumor development on MRI over a 5-year follow-up. Cobalt levels were significantly lower in the large-head group compared to the small-head group at 36, 48, and 60 months postoperatively, while chromium levels were significantly lower in the large-head group compared to the small-head group at 12 and 48 months postoperatively. The incidence of moderate pseudotumor development was significantly lower in the large-head group compared to the small-head group.

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OrthoEvidence. Metal ions and moderate pseudotumor development reduced with large- vs. small-head MoM THA. ACE Report. 2018;8(9):18. Available from: https://myorthoevidence.com/AceReport/Report/

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