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Previous Ace Report Similar fusion success rate between i-Factor allograft and local autograft in single-level ACDF Next Ace Report Adherence to weekly oral BP therapy versus quarterly IV BP therapy at varying health literacy level
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Arthroplasty
Combined IV-IA TXA further reduces blood loss versus IV TXA alone, but does not reduce transfusion
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Arthroplasty
Combined IV-IA TXA further reduces blood loss versus IV TXA alone, but does not reduce transfusion
BMC Musculoskelet Disord. 2018 Sep 7;19(1):321. doi: 10.1186/s12891-018-2181-9
Contributing Authors

Y Wu B Shen Y Liu Y Zeng H Xiong

Six randomized controlled trials were included in this meta-analysis, which sought to compare efficacy and safety measures between combined intravenous and topical tranexamic acid administration and intravenous tranexamic acid administration alone in total knee arthroplasty. Pooled analyses on total blood loss and maximum hemoglobin drop significantly favoured combined IV-IA TXA groups, though no significant difference in the rate of transfusion was observed. Rate of deep vein thrombosis also did not significantly differ between groups.

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OrthoEvidence. Combined IV-IA TXA further reduces blood loss versus IV TXA alone, but does not reduce transfusion. ACE Report. 2019;9(2):112. Available from: https://myorthoevidence.com/AceReport/Report/

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