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Previous Ace Report OTA2018: Equivalence not demonstrated, higher union with ICBG vs. rhBMP-2 for open tibial fracture Next Ace Report OTA2018: Nonsignficant reduction in pain, opioid consumption with PAI in fixation of ankle fracture
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OTA2018: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis
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Trauma
OTA2018: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis

Contributing Authors

G Slobogean RV O'Toole T Manson NN O'Hara B Haac R van Besien D Stein H Johal R Castillo P Berger B Reahl D Marinos Y Degain D Mascarenhas D Connelly T Scalea

329 patients with an operative extremity fracture, or pelvic and/or acetabular fracture and required thromboprophylaxis were randomized to either low molecular weight heparin 30mg twice daily or aspirin 81mg twice daily for 90 days. Patients were followed up for bleeding events and venous thromboembolic complications. Results demonstrated no significant differences between groups in rates of either bleeding events, pulmonary embolism, or deep vein thrombosis. However, in subgroup analysis among patients with concomitant abdominal injury, rate of bleeding events was significantly lower in those administered low molecular weight heparin.

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OrthoEvidence. OTA2018: Similar efficacy and safety of LMWH 30mg BID and aspirin 81mg BID for VTE prophylaxis. ACE Report. 2018;8(10):72. Available from: https://myorthoevidence.com/AceReport/Report/

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