
Arthroplasty
Similar blood loss, Hb drop, and transfusion rate between oral and IV TXA in minimally invasive THA
Int Orthop. 2018 Nov;42(11):2535-2542. doi: 10.1007/s00264-018-3846-6120 patients scheduled for total hip arthroplasty through a direct anterior approach were randomized to one of three groups: oral tranexamic acid administration, intravenous tranexamic acid administration, or control. The purpose of this study was to compare blood loss parameters, transfusion measures, and incidence of complications between the three groups. Results demonstrated significant differences in favour of both the oral TXA group and the IV TXA group compared to the control group for hemoglobin drop, total blood loss, and transfusion rate, while there were no significant differences between the two TXA groups. No patient in either of the three groups experienced a venous thromboembolic complication event.
Unlock the full article
Get unlimited access to OrthoEvidence with a free trial
Start TrialCritical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or continue reading this full article
Register Now

Subscribe to "The Pulse"
Evidence-Based Orthopaedics direct to your inbox.