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No significant effect of topical FS or TXA on blood loss in cases of sub-capital femoral fracture
Arch Orthop Trauma Surg. 2019 May;139(5):597-604. doi: 10.1007/s00402-018-3089-4

161 patients with a sub-capital femoral fracture and undergoing arthroplasty were randomized to one of three groups: topical fibrin sealant application, topical tranexamic acid applications, or standard haemostasis through electrocoagulation alone. The primary outcome of this study was volume of blood loss to postoperative drainage. Results demonstrated no significant differences between the three groups in the primary outcome, or in secondary outcomes of total blood loss, hidden blood loss, haemoglobin level, and rate of patients who required transfusion.

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OrthoEvidence. No significant effect of topical FS or TXA on blood loss in cases of sub-capital femoral fracture. ACE Report. 2019;9(6):11. Available from: https://myorthoevidence.com/AceReport/Report/

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