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ARTHROPLASTY
COA/ICORS2019: No difference between dexmedetomidine and epinephrine for block extension in TKA

70 patients scheduled for total knee arthroplasty and were managed with multimodal analgesia consisting of a continuous adductor canal block, single shot lateral femoral cutaneous nerve block, and posterior infiltration were randomized to either additional dexmedetomidine or epinephrine to a solution of ropivacaine, morphine, and ketorolac. The purpose of this study was to determine if there was a significant difference in time to first rescue analgesia request between groups. Results demonstrated no significant difference between groups in time to first rescue analgesia request, or in mean pain scores or opioid consumption over the first 24 hours after surgery.

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  • Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
  • Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
  • Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
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OrthoEvidence. COA/ICORS2019: No difference between dexmedetomidine and epinephrine for block extension in TKA. ACE Report. 2019;9(6):25. Available from: https://myorthoevidence.com/AceReport/Report/

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