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Benefit of BM-MSC addition in core decompression in treatment of osteonecrosis of the femoral head
Int J Surg. 2019 Jul 10;69:23-31
Contributing Authors

Z Wang QM Sun FQ Zhang QL Zhang LG Wang WJ Wang

14 randomized controlled trials were included in this meta-analysis which sought to investigate the impact of autologous bone marrow-derived mesenchymal stem cell (MSC) administration alongside core decompression on outcomes in treatment of patients with osteonecrosis of the femoral head. Pooled analyses of pain scores from 6 months to 2 years, function from 1 to 2 years, and incidence of eventual total hip arthroplasty, ranging from 1 to 5 years in the same analysis, all significantly favoured MSC groups compared to control groups.

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OrthoEvidence. Benefit of BM-MSC addition in core decompression in treatment of osteonecrosis of the femoral head. ACE Report. 2019;9(8):9. Available from: https://myorthoevidence.com/AceReport/Report/

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