GENERAL ORTHOPAEDICS
OTA 2019: Feasibility trial comparing IFF to DFR for distal femoral fractures in osteoporotic elders
23 patients across 7 centers were recruited to a feasibility study investigating the differences between internal fracture fixation (IFF) and distal femoral replacement (DFR) and the viability of a full scale randomized trial. Outcomes of interest included the EuroQol-5 Dimensions (EQ-5D) questionnaire at 6 months post-injury (primary), in-patient costs and estimates of standard deviation to inform sample size calculations. Results revealed favourable EQ-5D scores and lower in-patient costs in the IFF group compared to the DFR group. Sample size calculations determined a minimum 1400 patients required for a full-scale, adequately powered randomized trial.
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