Multiple peri-operative pain management strategies exist for patients undergoing total knee arthroplasty. These options include epidural analgesia, femoral nerve block, periarticular infiltration, and adductor canal block, which has gained recent prominence. Recent evidence has shown mixed results when comparing adductor canal block to the other local anesthetic options. In this study, the authors randomized 100 patients to receive either an adductor canal block or periarticular infiltration. Patients receiving periarticular infiltration had significantly lower pain scores at 6, 12, and 24 hours post-operatively. Opioid use was not measured as an outcome.