Ninety-eight patients scheduled for an anterior cruciate ligament reconstruction with a semitendinosus autograft were randomized to receive femoral tunnel placement using a transtibial, transportal or outside-in technique. Outcomes of interest were radiographic in nature, including femoral tunnel length, femoral and tibial tunnel angles, femoral tunnel position and tibial tunnel position. Computed tomography scans were performed 3 weeks after surgery. Results of the study found the transtibial technique to result in significantly higher femoral tunnel positions with larger variance compared to the transportal and outside-in techniques. Several patients in the transtibial group could not achieve femoral tunnel placement in the intended position.