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Osteoarthritis
Clinical benefit of intraarticular saline as a comparator in clinical trials of knee osteoarthritis

Semin Arthritis Rheum. 2016;46(2):151-9

Contributing Authors

R Altman Altman R Devji T Bhandari M Fierlinger A Niazi F Christensen R

Thirty-eight studies comparing intra-articular (IA) saline to either IA hyaluronic acid, IA corticosteroid or platelet-rich plasma in patients with symptomatic knee osteoarthritis (OA) were included in this meta-analysis. The primary outcome was the short-term (3 months or less) and long-term (6-16 months) pain reduction. Treatment-related adverse events (TRAEs) were also extracted and categorized as either serious or non-serious.

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OrthoEvidence. Clinical benefit of intraarticular saline as a comparator in clinical trials of knee osteoarthritis. ACE Report. 2020;():. Available from: https://myorthoevidence.com/AceReport/Report/

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