
Arthroplasty
Rivaroxaban offers effective extended thromboprophylaxis than enoxaparin after THA
Lancet. 2008 Jul 5;372(9632):31-9. Epub 2008 Jun 242509 patients (>18 yr old) scheduled to undergo elective total hip arthroplasty were randomized to receive either oral rivaroxaban or enoxaparin to compare both methods of thromboprophylaxis. After a 42 day follow up, extended thromboprophylaxis with rivaroxaban was significantly more effective than short-term enoxaparin plus placebo for the prevention of venous thromboembolism, including symptomatic events, in patients undergoing total hip arthroplasty.
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