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Previous Ace Report Antegrade and retrograde nailing clinically equivalent for mid-shaft humeral fractures Next Ace Report Antegrade and retrograde nailing clinically equivalent for mid-shaft humeral fractures
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General Orthopaedics
Biochemical markers of bone and cartilige degradation associated with progression of OA
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General Orthopaedics
Biochemical markers of bone and cartilige degradation associated with progression of OA
Osteoarthritis Cartilage. 2008 Jun;16(6):660-6. Epub 2007 Nov 13.
Contributing Authors

P Garnero WS Aronstein SB Cohen PG Conaghan GA Cline C Christiansen JF Beary JM Meyer Bingham CO

2483 patients were recruited to two parallel studies in North America (NA) and Europe (EU) to assess the effect of the structure modifying anti-OA drug, risedronate, on bone and cartilage degradation markers and radiological progression of OA. At 6 months, there was a dose-dependent induced reduction in markers of cartilage and bone degradation that was maintained until 24 months follow-up. Radiological progression of knee OA, as measure by change in joint space width (JSW), was associated with CTX-II levels throughout the study.

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OrthoEvidence. Biochemical markers of bone and cartilige degradation associated with progression of OA. ACE Report. 2013;3(3):285. Available from: https://myorthoevidence.com/AceReport/Report/

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