OSTEOARTHRITIS
Cross-linked formulation of hyaluronic acid provides long term pain relief
Osteoarthritis Cartilage. 2012 May;20(5):350-6. Epub 2012 Feb 1379 patients with osteoarthritis of the knee who had joint aspiration were randomized to receive a single injection of Gel-200 (new cross-linked hyaluronic acid product) or phosphate buffered saline (PBS) solution. Results from 13 week follow-up revealed that patients who received Gel-200 had significantly better pain scores and functions. Additionally, the two groups did not significantly differ in regards to adverse events.
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