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Single bisphosphonate infusion does not speed up fracture healing in high tibial osteotomy
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Osteoarthritis
Single bisphosphonate infusion does not speed up fracture healing in high tibial osteotomy
Acta Orthop. 2011 Aug;82(4):465-70. Epub 2011 Jun 21

46 patients with knee osteoarthritis undergoing high tibial osteotomies were randomized 4 weeks postoperatively to receive a single bisphosphonate infusion of zoledronic acid or a sodium chloride placebo. The primary outcome was reduction in healing time. Other outcomes included hip knee ankle (HKA) angle and patient-relevant outcome measures (Knee injury and osteoarthritis outcomes score (KOOS)). Results indicated that a single bisphosphonate infusion intervention does not accelerate healing in high tibial osteotomies.

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OrthoEvidence. Single bisphosphonate infusion does not speed up fracture healing in high tibial osteotomy. ACE Report. 2013;3(8):247. Available from: https://myorthoevidence.com/AceReport/Report/

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