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Previous Ace Report Use of wound drain after unilateral total knee arthroplasty Next Ace Report Use of wound drain after unilateral total knee arthroplasty
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Arthroplasty
TKR: blood conservation similar between one and two injections of tranexamic acid
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Arthroplasty
TKR: blood conservation similar between one and two injections of tranexamic acid
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This report has been verified by one or more authors of the original publication.
J Bone Joint Surg Br. 2012 Jul;94(7):932-6
Contributing Authors

PC Lin CH Hsu CC Huang WS Chen JW Wang

151 patients undergoing unilateral minimally invasive total knee replacement (TKR) were randomized to receive either one-dose of tranexamic acid (TEA) (10 mg/kg), two-doses TEA (10 mg/kg), or a placebo. The primary outcome was total blood loss, measured by maximum loss of haemoglobin (Total blood loss = (Total blood volume x [change in haemoglobin level / mean haemoglobin]) + volume transfused) . Results indicated that blood conservation after TKR was effective and adequate with one intraoperative injection of tranexamic acid (TEA).

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OrthoEvidence. TKR: blood conservation similar between one and two injections of tranexamic acid. ACE Report. 2013;3(8):253. Available from: https://myorthoevidence.com/AceReport/Report/

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