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General Orthopaedics
Fenofibrate produces a reduction in amputation events in type II diabetics
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General Orthopaedics
Fenofibrate produces a reduction in amputation events in type II diabetics
Lancet. 2009 May 23;373(9677):1780-8
Contributing Authors

K Rajamani PG Colman LP Li JD Best M Voysey MC D'Emden M Laakso JR Baker AC Keech FIELD study investigators

9795 patients with type II diabetes were randomized to receive daily treatment with 200 mg of fenofibrate or equivalent placebo treatment. This study examined the effect of a long-term lipid-lowering treatment on occurrence of amputation and reduction of adverse outcomes of the macro- and micro-vasculature. At 5 year follow-up, fenofibrate produced a reduction in non-traumatic amputations observed in type II diabetics.

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OrthoEvidence. Fenofibrate produces a reduction in amputation events in type II diabetics. ACE Report. 2013;3(5):82. Available from: https://myorthoevidence.com/AceReport/Report/

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