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ARTHROPLASTY
Single-dose epidural DepoDur is a safe and effective analgesic after knee arthroplasty
J Bone Joint Surg Am. 2006 Feb;88(2):273-81
Contributing Authors

CT Hartrick G Martin G Kantor J Koncelik G Manvelian

168 patients were randomised to receive either a single-dose, extended-release epidural morphine formulation intervention (DepoDur) at 20 or 30 mg, or a sham epidural injection after undergoing elective unilateral knee arthroplasty. The primary outcomes were pain and safety. Results indicated that the DepoDur intervention provided a safe and efficacious method of analgesia for patients up to 48 hours after undergoing knee arthroplasty.

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OrthoEvidence. Single-dose epidural DepoDur is a safe and effective analgesic after knee arthroplasty. ACE Report. 2013;3(8):470. Available from: https://myorthoevidence.com/AceReport/Report/

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