ARTHROPLASTY
Knee ACI: No clinical outcome differences between periosteal and collagen membrane cover
This report has been verified
by one or more authors of the
original publication.
Knee. 2006 Jun;13(3):203-10. Epub 2006 Apr 27
68 patients with symptomatic articular cartilage defects in the knee were randomized to receive autologous chondrocyte implantation with a periosteal cover (ACI-P) or a type I/III collagen membrane (ACI-C). After a follow up period of 24 months, there was no significant difference in clinical outcome between the two groups. However, a significant amount of the ACI-P patients required shaving of a hypertrophied graft after 1 year, compared to none in the ACI-C group. Overall, the results of the study determined that the effectiveness of a type I/III collagen membrane is comparable to a periosteal cover in promoting hyaline cartilage repair.
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