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Metabolic Disorders
Effects of ch-OSA and Ca/Vit D3 administration in osteopenic women
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Metabolic Disorders
Effects of ch-OSA and Ca/Vit D3 administration in osteopenic women
BMC Musculoskelet Disord. 2008 Jun 11;9:85
Contributing Authors

Tim D Spector Mario R Calomme Simon H Anderson Gail Clement Liisa Bevan Nathalie Demeester Rami Swaminathan Ravin Jugdaohsingh Dirk A Vanden Berghe Jonathan J Powell

184 osteopenic (T-score spine < -1.5) caucasian women all received daily administration of 1000 mg Ca and 20 microg cholecalciferol (Vit D3). In addition, the women were randomized to receive either oral choline-stabilized orthosilicic acid (ch-OSA) or placebo treatment for 1 year. 136 women completed the study. At 1 year, the combined therapy of ch-OSA and Ca/Vit D3 demonstrated a potential beneficial effect on bone type I collagen formation (PINP) that was significant at 12 months for the 6 and 12 mg Si dose compared to Ca/Vit D3 treatment alone.

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OrthoEvidence. Effects of ch-OSA and Ca/Vit D3 administration in osteopenic women. ACE Report. 2013;3(3):259. Available from: https://myorthoevidence.com/AceReport/Report/

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