General Orthopaedics
Chaperonin 10: Short term relief for rheumatoid arthritis patients
Lancet. 2006 Dec 2;368(9551):1964.23 patients with moderate to severe active rheumatoid arthritis were randomized to receive either 5 mg, 7.5 mg, or 10 mg of Chaperonin 10, an anti-inflammatory drug, intravenously twice weekly for 12 weeks. Disease activity score and core disease measures were assessed throughout the course of the study. By the end of the 12 week study, it was determined that improvement in rheumatoid arthritis was found in all three treatment groups with the 10 mg group having consistently better outcome scores than the 5 mg and 7.5 mg groups.
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