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TKA: Topical fibrin spray significantly reduces total blood loss
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Arthroplasty
TKA: Topical fibrin spray significantly reduces total blood loss
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Knee. 2012 Aug;19(4):295-8. Epub 2011 Jul 5

66 patients undergoing navigated, cemented total knee arthroplasty were randomized to one of three groups to compare the efficacy of two different haemostatic agents on total blood loss. Patients received a 10mg/kg bolus of tranexamic acid intravenously, topical fibrin spray, or no additional haemostatic treatment (control). The results indicated that both haemostatic agents produced a reduction in total blood loss compared to controls: however, this reduction was only significant in the fibrin spray group.

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OrthoEvidence. TKA: Topical fibrin spray significantly reduces total blood loss. ACE Report. 2013;3(5):20. Available from: https://myorthoevidence.com/AceReport/Report/

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