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Metabolic Disorders
Osteoporosis: Zoledronic acid increases bone mineral density and reduces fracture rate
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Metabolic Disorders
Osteoporosis: Zoledronic acid increases bone mineral density and reduces fracture rate
Asian Pac J Trop Med. 2012 Sep;5(9):743-8. doi: 10.1016/S1995-7645(12)60118-7
Contributing Authors

J Zhang R Wang YL Zhao XH Sun HX Zhao L Tan DC Chen X Hai-Bin

This meta-analysis included 9 studies comparing zoledronic acid and a placebo in patients with osteoporosis. Results from the analysis indicated that zoledronic acid was effective in increasing bone mineral density and reducing fracture rate. The zoledronic acid group also demonstrated a significantly lower rate of serious adverse events than the control group. According to subgroup analyses, older patients (over 50 years) and those who received the intervention longer (more than 12 months) benefited most from zoledronic acid.

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OrthoEvidence. Osteoporosis: Zoledronic acid increases bone mineral density and reduces fracture rate. ACE Report. 2013;3(8):323. Available from: https://myorthoevidence.com/AceReport/Report/

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