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Previous Ace Report Plate fixation superior to pin fixation for intra-articular distal radius fracture Next Ace Report Plate fixation superior to pin fixation for intra-articular distal radius fracture
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Osteosarcoma: 25 year survival rate significantly improved with adjuvant chemotherapy
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Osteosarcoma: 25 year survival rate significantly improved with adjuvant chemotherapy
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This report has been verified by one or more authors of the original publication.
Cancer. 2012 Dec 1;118(23):5888-93
Contributing Authors

NM Bernthal N Federman FR Eilber SD Nelson JJ Eckardt FC Eilber WD Tap

59 patients who underwent treatment for stage IIA/IIB, intramedullary, high-grade osteosarcoma, between 1981 and 1984, were randomized to receive either T-10B protocol adjuvant chemotherapy or no adjuvant chemotherapy following definitive surgical resection. Improvements in disease-free survival (DFS) and overall survival (OS) were monitored over 25 years, and tumor necrosis was evaluated for implications in prognosis. Results demonstrated a significant improvement in DFS and OS in patients who received adjuvant chemotherapy.

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OrthoEvidence. Osteosarcoma: 25 year survival rate significantly improved with adjuvant chemotherapy. ACE Report. 2013;3(4):12. Available from: https://myorthoevidence.com/AceReport/Report/

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