
Arthroplasty
TKA: Intra-articular tranexamic acid reduces blood loss and transfusion requirements
This report has been verified
by one or more authors of the
original publication.
Knee Surg Sports Traumatol Arthrosc. 2012 Dec;20(12):2494-501. doi: 10.1007/s00167-012-1942-5. Epub 2012 Mar 15
Fifty patients with knee osteoarthritis undergoing primary unilateral cemented-TKA were randomized to receive either intra-articular tranexamic acid (TA) or saline solution (control). After the first 48 hours, the parameters related to the drain output were compared between the two groups. Blood loss on 5th post-operative day was also noted. Results demonstrated that patients who received tranexamic acid obtained a noticeable reduction in drain output and showed a lower drop in haemoglobin and haematocrit than the control group.
Unlock the full article
Get unlimited access to OrthoEvidence with a free trial
Start TrialCritical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or continue reading this full article
Register Now

Subscribe to "The Pulse"
Evidence-Based Orthopaedics direct to your inbox.