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TKA: Intra-articular tranexamic acid reduces blood loss and transfusion requirements
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Arthroplasty
TKA: Intra-articular tranexamic acid reduces blood loss and transfusion requirements
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Knee Surg Sports Traumatol Arthrosc. 2012 Dec;20(12):2494-501. doi: 10.1007/s00167-012-1942-5. Epub 2012 Mar 15
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SP Roy UF Tanki A Dutta SK Jain ON Nagi

Fifty patients with knee osteoarthritis undergoing primary unilateral cemented-TKA were randomized to receive either intra-articular tranexamic acid (TA) or saline solution (control). After the first 48 hours, the parameters related to the drain output were compared between the two groups. Blood loss on 5th post-operative day was also noted. Results demonstrated that patients who received tranexamic acid obtained a noticeable reduction in drain output and showed a lower drop in haemoglobin and haematocrit than the control group.

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OrthoEvidence. TKA: Intra-articular tranexamic acid reduces blood loss and transfusion requirements. ACE Report. 2013;3(5):156. Available from: https://myorthoevidence.com/AceReport/Report/

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