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METABOLIC DISORDERS
Tranexamic acid reduces blood transfusion requirements during surgery
BMJ. 2012 May 17;344:e3054. doi: 10.1136/bmj.e3054
Contributing Authors

K Ker P Edwards P Perel H Shakur I Roberts

In this systematic review 129 trials (consisting of 10488 participants) examining the effectiveness of tranexamic acid during surgery to a placebo or no acid were evaluated. Results displayed that tranexamic acid reduced the chances of needing a blood transfusion in surgical patients. Yet, there was not enough evidence to determine the effects of tranexamic acid on thromboembolic events and mortality in patients undergoing surgery.

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  • Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
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  • Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
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OrthoEvidence. Tranexamic acid reduces blood transfusion requirements during surgery. ACE Report. 2013;3(8):585. Available from: https://myorthoevidence.com/AceReport/Report/

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