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General Orthopaedics
TNF antagonist better in treatment of early rheumatoid arthritis
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General Orthopaedics
TNF antagonist better in treatment of early rheumatoid arthritis
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This report has been verified by one or more authors of the original publication.
Lancet. 2009 Aug 8;374(9688):459-66.
Contributing Authors

RF van Vollenhoven S Ernestam P Geborek IF Petersson L Cöster E Waltbrand A Zickert J Theander A Thörner H Hellström A Teleman C Dackhammar F Akre K Forslind L Ljung R Oding A Chatzidionysiou M Wörnert J Bratt

258 patients with early stage rheumatoid arthritis, who were unresponsive to 4 months treatment with methotrexate, were randomized to receive additional treatment with Infliximab (tumor necrosis factor antagonist) or sulfasalazine and hydroxychloroquine. This trial assessed the efficacy of the use of tumor necrosis factor antagonists in treatment of rheumatoid arthritis, while comparing this treatment to other antirheumatic drugs. The results from this trial indicated that Inifliximab produced a greater number of improved patients when compared to the sulfasalazine and hydroxychloroquine group.

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OrthoEvidence. TNF antagonist better in treatment of early rheumatoid arthritis . ACE Report. 2013;3(5):126. Available from: https://myorthoevidence.com/AceReport/Report/

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