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Low-dose tranexamic acid does not reduce blood loss or transfusion rate in spinal surgery
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Low-dose tranexamic acid does not reduce blood loss or transfusion rate in spinal surgery
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J Neurosurg Anesthesiol. 2011 Oct;23(4):290-6. doi: 10.1097/ANA.0b013e31822914a1

76 patients scheduled for spinal fixation surgery were randomized to receive prophylactic low-dose tranexamic acid (TXA) or placebo saline to determine the efficacy of TXA on the reduction of perioperative blood loss and blood transfusion. The results indicated that the administration of TXA led to no appreciable blood loss of transfusion reduction compared to saline.

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OrthoEvidence. Low-dose tranexamic acid does not reduce blood loss or transfusion rate in spinal surgery. ACE Report. 2013;3(11):25. Available from: https://myorthoevidence.com/AceReport/Report/

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