
OSTEOARTHRITIS
Diacerein paired with diclofenac sodium improves pain and function in knee OA patients
This report has been verified
by one or more authors of the
original publication.
Int J Rheum Dis. 2012 Feb;15(1):69-77. doi: 10.1111/j.1756-185X.2011.01648.x. Epub 2011 Sep 6
74 patients were randomized to assess the clinical effectiveness of diacerein as an adjuvant to diclofenac sodium for the treatment of knee osteoarthritis (OA). Patients received diclofenac sodium 75 mg once daily with either capsule diacerein 50 mg or matched placebo once daily for the first month and twice daily for the next 2 months. Results at 4 months revealed that the use of diacerein with diclofenac sodium was significantly more effective in improving pain and joint function compared to diclofenac alone.
Unlock the full ACE Report
You have access to {0} free articles per month.Click below to unlock and view this {1}
Unlock NowCritical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidence content for just $1.99 per week.
Already have an account? Log in


Subscribe to "The Pulse"
Evidence-Based Orthopaedics direct to your inbox.
{0} of {1} free articles
Become an OrthoEvidence Premium Member. Expand your perspective with high-quality evidence.
Upgrade Now