
Sports Medicine
The use of zolpidem for outpatient ACL reconstruction reduces narcotic consumption
Knee Surg Sports Traumatol Arthrosc. 2011 May;19(5):787-91. doi: 10.1007/s00167-010-1368-x. Epub 2011 Jan 2129 patients were randomized to assess the effect of a non-benzodiazepine hypnotic sleep-aid, Zolpidem, on postoperative narcotic requirements, pain, and fatigue in patients undergoing outpatient anterior cruciate ligament (ACL) reconstruction. Patients received either a single dose of Zolpidem or a gelatin capsule (placebo) for the first seven postoperative nights. Results indicated that Zolpidem reduced the total amount of narcotic consumption by 28% when compared to the placebo. However, no significant differences were observed between both groups regarding postoperative pain or fatigue levels.
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