32 patients with bilateral knee osteoarthritis (OA) were randomized to receive either computer-assisted navigation total knee arthroplasty or conventional total knee arthroplasty. Each patient received treatment on both knees, with each intervention being performed on separate knees. Randomization occurred on the basis of operative technique and on which treatment was preformed first. The results of the 6-month follow up indicated that computer-assisted total knee arthroplasty was significantly more accurate at aligning the knee prosthesis in the coronal and sagittal planes within 3 degrees. Additionally, it was found that the computer-assisted intervention was significantly longer in comparison to conventional knee arthroplasty by an average of 30 minutes.