54 patients with chronic midportion Achilles tendinopathy undergoing an eccentric exercise programme were randomized to receive either a platelet-rich plasma (PRP) injection or a saline injection (placebo), in order to determine whether PRP injections would result in enhanced tendon structure and neovascularisation that could be observed through ultrasonographic methods. Following evaluations over a 24 week period, the results indicated that no significant differences existed in neovascularisation scores between groups and that PRP injections did not contribute to improved tendon structure.