GENERAL ORTHOPAEDICS
Positive effect of D-003 on bone mineral density in postmenopausal women
Korean J Intern Med. 2011 Jun;26(2):168-78. doi: 10.3904/kjim.2011.26.2.168. Epub 2011 Jun 183 postmenopausal women with osteopenia or osteoporosis were randomized to determine the efficacy of D-003, an isolate from sugar cane wax, on improving bone mineral density (BMD). Participants were treated with either 10mg/day D-003 or placebo for 3 years. Results at the end of the trial indicated that lumbar spine BMD was significantly improved with D-003 compared to placebo. Women treated with D-003 also experienced an increase in femoral neck BMD, although the difference was not significantly different than that obtained by the placebo group.
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