Blood loss following total hip arthroplasty (THA) is an important procedural consideration. 204 patients who underwent primary THA were randomized to be managed by either combined intra-operative and post-operative autologous blood transfusion (ABT) or no-drainage. The purpose of the study was to determine the effect of each blood-sparing measure on blood loss, hemoglobin (Hb) level reduction, as well as the need for homologous blood transfusions. The results prior to discharge indicated that total blood loss was lower in the ABT group, and that the maximum drop in Hb level was less severe with ABT. However, mean daily post-operative Hb levels did not significantly differ, nor did the requirement for homologous blood transfusions.