OSTEOARTHRITIS
Limited efficacy of glucosamine preparations in the treatment of knee or hip OA
Int J Clin Pract. 2013 Jun;67(6):585-94. doi: 10.1111/ijcp.1211519 double-blind, placebo-controlled randomized controlled trials were included in this meta-analysis investigating the effect of glucosamine sulfate and glucosamine hydrochloride in the treatment of knee or hip osteoarthritis. Results indicated that neither preparation had a significant effect for pain reduction. Functional recovery appeared to be improved with glucosamine sulfate, specifically after 6 months of follow-up. Functional recovery was not examined in trials investigating the effect of glucosamine hydrochloride.
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