117 patients with knee osteoarthritis were randomized to undergo robotic total knee arthroplasty using either the classical or anatomical technique, the purpose of which was to compare the clinical and radiological outcomes of the two techniques. After 2 years of follow-up, results indicated that patients in both groups did not differ in range of motion (ROM), Hospital for Special Surgery (HSS), and Western Ontario and McMaster Universities (WOMAC) scores, mechanical axes, and varus and valgus laxities. Though, there were significant differences seen between groups for coronal alignments of the femoral and tibial components.