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Previous Ace Report Music-based multi-task training for older adults Next Ace Report No difference between single-, double-row suture anchor repair in rotator cuff tears
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Trauma
rhBMP-2 provides no benefit in treatment of open tibial fractures with a reamed IM nail
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Trauma
rhBMP-2 provides no benefit in treatment of open tibial fractures with a reamed IM nail
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This report has been verified by one or more authors of the original publication.
J Bone Joint Surg Am. 2011 May 4;93(9):801-8. Epub 2011 Mar 31.
Contributing Authors

HT Aro S Govender AD Patel P Hernigou A Perera de Gregorio GI Popescu JD Golden J Christensen A Valentin

277 patients with an open tibial shaft fracture were randomized to either receive the standard of care or to the treatment group, which received the standard of care plus implantation of a collagen sponge containing 12 mg of Recombinant human bone morphogenetic protein-2 (rhBMP-2). This study failed to detect any substantial benefit of the BMP treatment in accelerating fracture union in open tibial fractures treated with reamed intramedullary nail fixation.

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OrthoEvidence. rhBMP-2 provides no benefit in treatment of open tibial fractures with a reamed IM nail. ACE Report. 2013;3(8):349. Available from: https://myorthoevidence.com/AceReport/Report/

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