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Apixaban reduces major bleeding and is non-inferior when compared to enoxaparin for TKA
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Arthroplasty
Apixaban reduces major bleeding and is non-inferior when compared to enoxaparin for TKA
Thromb Haemost. 2011 Feb;105(2):245-53
Contributing Authors

J Huang Y Cao C Liao L Wu F Gao

Data from 3 randomized-controlled trials (7337 individuals) was analyzed to evaluate the efficacy of apixaban in the treatment of TKA complications of venous thromboemolisms (VTE) including deep-vein thrombosis (DVT) and pulmonary embolism (PE), when compared against enoxaparin. Complication incidence was analyzed, along with safety endpoints. The results of the meta-analysis demonstrated that apixaban performed comparably to enoxaparin with advantages in DVT incidence and reduction of major-bleeding.

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OrthoEvidence. Apixaban reduces major bleeding and is non-inferior when compared to enoxaparin for TKA. ACE Report. 2014;4(3):77. Available from: https://myorthoevidence.com/AceReport/Report/

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