Ace Report Cover
Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA
Reprints
Cite This
Reprints
Cite This
AceReport Image
Arthroplasty
Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA
Clin Orthop Relat Res. 2011 Oct;469(10):2874-80. Epub 2011 Apr 22

100 patients with primary osteoarthritis who were scheduled to undergo unilateral cemented total knee arthroplasty were randomized to receive either placebo or intravenous tranexamic acid 10 minutes prior to surgery, 3 hours after surgery, and orally for 5 days after surgery. Patients who received tranexamic acid displayed significantly less blood loss, hemoglobin loss, and required significantly less blood transfusion in comparison to patients who received placebo. Additionally, no changes were observed in symptomatic thromboembolic events.

Unlock the full article

Get unlimited access to OrthoEvidence with a free trial
Start Trial

Critical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics

Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics

Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions

Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics

Or continue reading this full article
Register Now
AskOE
Search
Close Search Window
Welcome Back!
Forgot Password?
Create an Account

Account will be affiliated with


OR
Forgot Password?

OR
Check your email

If an account exists with the provided email address, a password reset email will be sent to you. If you don't see the email, please check your spam or junk folder.

For further assistance, contact our support team.

Cite this Ace Report

OrthoEvidence. Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA. ACE Report. 2013;3(3):122. Available from: https://myorthoevidence.com/AceReport/Report/

Copy Citation
Share this Ace Report