31 patients (56 ankles) diagnosed with either haemophilia A or B and haemophilic arthropathy in one or both ankles were randomized to either a manual therapy, educational or control group, to determine whether the interventions in question improve clinical and functional outcomes in this population. Results indicated that, although both physiotherapy interventions were safe, only the manual therapy group displayed significantly improved gastrocnemius circumference and ankle pain upon completion of the program. These effects seemed to last up until the 6-month follow-up. Functional and clinical outcomes were not significantly improved in either the educational or control group at any time point.