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Arthroplasty
AAOS: Weighted and uniform doses of tranexamic acid similar in reducing blood loss in TKA
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Arthroplasty
AAOS: Weighted and uniform doses of tranexamic acid similar in reducing blood loss in TKA

Contributing Authors

M Belkin ZH Goldstein BR Levine

50 patients undergoing primary total knee arthroplasty were randomized to receive either a uniform 1-gram dose or a weighted 20 mg/kg dose of intravenous tranexamic acid. The purpose of this study was to determine whether a uniform dose would be more effective than a weighted dose, with respect to postoperative blood loss and hemoglobin levels. Results indicated that intraoperative, postoperative, and total blood loss were not significantly different between treatment groups, suggesting that the treatments were equally effective.

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OrthoEvidence. AAOS: Weighted and uniform doses of tranexamic acid similar in reducing blood loss in TKA. ACE Report. 2014;4(3):41. Available from: https://myorthoevidence.com/AceReport/Report/

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