ARTHROPLASTY
AAOS: Lower preoperative coagulation factors may correlate with transfusion risk in TJA
51 patients undergoing elective total knee and hip arthroplasty were randomized to receive thromboprophylaxis with either subcutaneous injection of fondaparinux (2.5 mg) or aspirin (325 mg) plus compression stockings. The purpose of this study was to determine whether a correlation exists between changes in thrombogenicity due to surgical trauma, and transfusion rates. Seven patients received a blood transfusion, and these patients had lower thrombin-induced platelet fibrin clot strength compared to patients who did not, at all time points. However, significance was only achieved prior to and immediately following surgery, suggesting a potential correlation. All other coagulation factors were not significant.
Unlock the full ACE Report
You have access to {0} free articles per month.Click below to unlock and view this {1}
Unlock NowCritical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or upgrade today and gain access to all OrthoEvidence content for just $1.99 per week.
Already have an account? Log in
Subscribe to "The Pulse"
Evidence-Based Orthopaedics direct to your inbox.
{0} of {1} free articles
Become an OrthoEvidence Premium Member. Expand your perspective with high-quality evidence.
Upgrade Now
