78 patients suffering from unilateral radicular pain were randomized to receive a transforaminal epidural steroid injection using either particulate (dexamethasone) and nonparticulate (triamcinolone) corticosteroid. The purpose was to evaluate if there were any differences between corticosteroid preparations over 6 months of follow-up. The evidence presented in this trial demonstrated comparable pain, function, and surgical rates associated with either treatment. Dexamethasone was associated with significantly more patients requiring more injections when compared to triamcinolone.