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The effect of bisphosphonates on indirect bone healing
J Orthop Surg Res. 2014 Jun 5;9:45
Contributing Authors

D Xue F Li G Chen S Yan Z Pan

Data from 8 randomized controlled trials (RCTs) investigating 2,508 patients were pooled to evaluate the effect of bisphosphonates on bone healing. Short- and long-term healing, and delayed fracture and nonunion data were analyzed along with other relevant outcomes. The evidence presented in this meta-analysis indicated that bisphosphonate treatment did not affect short- or long-term healing, delayed bone healing, and nonunion. Timing of zoledronic acid infusion did not affect bone healing.

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OrthoEvidence. The effect of bisphosphonates on indirect bone healing. ACE Report. 2014;4(9):10. Available from: https://myorthoevidence.com/AceReport/Report/

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