Data from 8 randomized controlled trials (RCTs) investigating 2,508 patients were pooled to evaluate the effect of bisphosphonates on bone healing. Short- and long-term healing, and delayed fracture and nonunion data were analyzed along with other relevant outcomes. The evidence presented in this meta-analysis indicated that bisphosphonate treatment did not affect short- or long-term healing, delayed bone healing, and nonunion. Timing of zoledronic acid infusion did not affect bone healing.
Unlock the full article
Get unlimited access to OrthoEvidence with a free trial
Start TrialCritical appraisals of the latest, high-impact randomized controlled trials and systematic reviews in orthopaedics
Access to OrthoEvidence podcast content, including collaborations with the Journal of Bone and Joint Surgery, interviews with internationally recognized surgeons, and roundtable discussions on orthopaedic news and topics
Subscription to The Pulse, a twice-weekly evidence-based newsletter designed to help you make better clinical decisions
Exclusive access to original content articles, including in-house systematic reviews, and articles on health research methods and hot orthopaedic topics
Or continue reading this full article
Register Now
Subscribe to "The Pulse"
Evidence-Based Orthopaedics direct to your inbox.
