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GENERAL ORTHOPAEDICS
Neuraxial block may be associated with a high risk for postoperative cardiac complications
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This report has been verified by one or more authors of the original publication.
Br J Anaesth. 2013 Sep;111(3):382-90. doi: 10.1093/bja/aet120. Epub 2013 Apr 23.
Contributing Authors

K Leslie P Myles P Devereaux E Williamson P Rao-Melancini A Forbes S Xu P Foex J Pogue M Arrieta G Bryson J Paul M Paech R Merchant P Choi N Badner P Peyton J Sear H Yang

7925 patients from the POISE trial were included in this post-hoc analysis regarding neuraxial block. The purpose of this analysis was to determine whether neuraxial block was significantly associated with the primary composite outcome (i.e., cardiovascular death, non-fatal myocardial infarction, or non-fatal cardiac arrest), myocardial infarction, stroke, and clinically-significant hypotension over 30 days post-operation. Results indicated that neuraxial block was associated with an increased risk for the primary composite outcome and myocardial infarction, but not stroke or death. There was a non-significant trend towards neuraxial block being associated with clinically-significant hypotension, and the administration of beta-blockers did not influence these results.

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OrthoEvidence. Neuraxial block may be associated with a high risk for postoperative cardiac complications. ACE Report. 2014;4(10):67. Available from: https://myorthoevidence.com/AceReport/Report/

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